Lesion is a weapon best built for Status. Throwing on the Dual Stat Mods can get you to 100%, and with its low Crit Chance, this is most likely the way you want to go. Raising your Status Chance increases your chance for some other benefits as well. When Lesion lands a Status Proc, it will receive 15% attack speed boost for 6s as well as a +100% Toxin Damage buff. Looking at the attack speed first, you should note it does combine mod effects but does not stack or refresh with repeated Procs. The attack speed buff timer must first run out before it will activate again. On the Toxin Damage side, the boost will combine with Primary and Secondary Elements you have modded for. This also synergises well with Saryn ,who buffs Status Proc Duration by 25%, meaning more Damage Over Time. And with her Toxic Lash, you’ll land that Status Proc with Ability Damage stacking with Lesion’s bonus Toxin Damage.